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Glossary of skin care ingridence
By James E. Fulton, JR., M.D., Ph.D.
 

Abrading: removing by friction, that is, by the wear and tear of scraping or grinding.
Acne vulgaris: common acne. We dislike the term “vulgaris.”
Antibacterial: substance that either destroys bacteria or somehow suppresses them; perhaps by cutting down on their production rate.
Antibiotic: substance produced by microorganisms that destroy or inhibit other competitive microorganisms.
Astringent: substance that contracts, dries, shrivels, or otherwise “tightens up” the surface upon which it is placed.

 

Bacteriostatic: substance that inhibits (without necessarily killing) bacteria.
Benzoyl peroxide: a powerful oxidant formulated for use in the treatment of acne. When applied daily, benzoyl peroxide diffuses into the skin and kills the bacteria that aggravates the acne problem.
Blackhead: open comedo; small plug of cellular debris and oil clogging a sebaceous follicle.
Bland: soothing or mild.
Broad-spectrum antibiotic: antibiotic which affects a wide range of different disease-causing microorganisms.

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Closed-comedo-“maturation-arrest” acne: acne condition in which the comedones remain closed and do not develop further or mature. That is, their progress is “arrested” or stopped.
Collagen: principal supportive protein of skin, cartilage, tendon, bone, and connective tissue.
Comedo: (plural-comedones) literally, glutton (perhaps because the ancients believed it was a maggot, devouring the flesh).
Comedo extractor: simple clinical instrument used for popping out the contents of acne lesions.
Corynebacterium acnes: bacterial organism associated with sebaceous follicles.
Cosmetic acne: acne induced by certain irritating facial “beauty” preparations commonly called cosmetics.
Cyst: walled sac or pouch formed when cells in the sebaceous follicles sludge up and become impacted.

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Dermabrasion: mechanical abrading or rubbing away of skin, usually with high-speed rotary brushes or fine abrasive matter (such as diamond particles).
Dermatologist: physician specialized in skin problems.
Dermis: bed of vascular connective tissue underlying the epidermis.
Dihydrotestosterone: a derivative of testosterone believed to be responsible for increased sebum production in the sebaceous glands.

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Enzyme: organic catalyst produced by living cells of the body; enzymes stimulate or accelerate biochemical reactions at the body’s normal temperature.
Epidermis: the outermost layer of skin.
Erythromycin: an antibiotic discovered in the metabolic products of bacteria of a Streptomyces erythreus strain which came from soil in the Philippine archipelago.
Escherichia coli: short, rod-shaped microorganisms accounting for most of our gut microorganisms.
Estrogen: hormone which promotes estrus (i.e., the sexual cycle) and the appearance of secondary sex characteristics in females.

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Follicle: excretory or secretors sac or gland; facial pores are follicular openings.
Food and Drug Administration: the national regulatory agency responsible for the purity and safety of food, drugs, and other products.
Free fatty acid: irritating byproduct formed when C. acnes breaks down triglycerides.

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Germinative layer: bottom layer of actively reproducing epidermal cells.
Glycerol: sweet, syrupy alcohol made from fats; specifically, the energy source which C. acnes provides enzymatically for itself by decomposing triglycerides of the sebum.

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Hormones: chemicals elaborated by living cells and which circulate to places in the body far from where they are made before exerting their effects on other cells.

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Impaction: clogged up contents (pus, cellular debris, skin fragments) of a comedo.
Infantile (or neonatal) acne: acne that occurs in an infant after birth; especially male children of acne-prone families. The problem clears up when the residual hormones from the mother are metabolized away, but reappears when the child’s own hormones are produced around the age of puberty.

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Keratin: a very insoluble protein found in hair, nails, epidermis, horny tissues, and tooth enamel.
Keratinization: transformation of cellular materials into keratin.
Keratinocyte: epidermal cell which synthesizes keratin.
Keratolytic: substance that dissolves, peels, or otherwise breaks up, or loosens keratin.

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Lesion: wound, sore, pustule, cyst, or any visible spot on the skin that is not normally present.
Lipase: enzyme involved in the splitting of lipids; for example, the splitting of triglycerides into glycerol and fatty acids by the bacteria of the skin.
Liquid nitrogen: nitrogen gas compressed under great pressure until it liquefies. If released from pressure, it evaporates rapidly, freezing whatever surface from which it evaporates.

 

Metabolism: biochemical transformation utilizing nutrients for building and maintaining the body, and, in short, the chemical mechanisms of growing and functioning as a living being.
Micro-comedo: tiny comedones, perhaps not yet even perceptible.
Moisturizer: substance that humidifies and softens the skin, making it more pliable and less likely to crack or peel unduly.

 

Neomycin: antibiotic produced by a Streptomyces microorganism.
Neonatal (or infantile) acne: acne that occurs in an infant after birth; especially male children of acne-prone families. The problem clears up when the residual hormones from the mother are metabolized away, but reappears when the child’s own hormones are produced around the age of puberty.

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Pancake make-up: dry cosmetic usually molded into “cakes” or solid discs, and applied by daubing a moist sponge onto the cake to pick up the cosmetic and transfer it to the skin.
Papule: literally, small swelling; solid lesion raised above the surface of the skin.
Papulo-pustular acne: papules and pustules together; the more inflamed forms of acne.
Panoxyl: commercial preparation of benzoyl peroxide.
Penicillin: antibiotic substance produced by molds of the Penicillium genus.
Placebo: a control, inactive substance (especially with no effect of its own) against which a “real” medication may be tested in a patient. The “real” medication is supposed to give the desired effect, while a placebo does nothing. However, a patient who claims the placebo is doing something, may be telling the truth.
Some people are ready to believe in any “medicine.” (In fact, placebo is Latin for I please, and was indeed given by physicians just to satisfy the patient that something was being done to help.)
Polymyxin: antibiotic produced by Bacillus polymyxin, a soil bacterium.
Protein: nitrogenous, amino-acid compounds. They occur in our cell protoplasm or are excreted by the cells; for example milk protein.
Potentiate: to make more powerful.
Puberty: age at which a person is first capable of sexual reproduction.
Purgative: strong laxative.
Pus: white cells (leukocytes) from the blood; concentrated to engulf and digest harmful substances in our bodies . . . or, more scientifically, a liquid containing leukocytes that accumulates in response to an infection or inflammation.
Pustule: small boil or abscess; pus-filled lesion raised above the surface of the skin.

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Retention hyperkeratosis: newly formed cells accumulating and retained in an ever-thickening layer down along the follicle wall.

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Sebaceous glands: skin-deep structures associated with the follicles; producing sebum.
Sebum: tallow or grease-like secretion of sebaceous glands; contain fat and cellular debris.
Senile acne: residual scars and old, trapped cysts (in persons beyond the “adolescent acne age”) that may flare up occasionally.
Sloughing: dead skin being separated from living skin.
Steroids: a family of chemical substances which include the sex hormones (androgen, estrogen), bile acids, toad poisons, etc.
Stratum corneum: dead and sloughing cells making up the outermost layer of epidermis.
Sulfur: yellowish, non-metallic element that burns with an acrid, blue flame.

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Testosterone: hormone, produced by the testes, that induces and maintains male secondary sex characteristics (beard, voice, etc.).
Tetracycline: parent compound of several antibiotics produced by the soil bacteria Streptomyces.
Topical drug: a drug whose effect is exerted through the skin; topical drugs are applied as ointments, wet compresses, lotions, etc.
Triglyceride: fat which makes up about 50% of sebum.

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Ultraviolet light: invisible radiation beyond the violet end (or band) of the visible light spectrum.

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Vitamin A acid: an irritant which effectively removes cellular sludge but does not build up tolerance nor require increased dosages to keep up the desirable effect.
Vitamin B12: a substance that contributes to the formation and functioning of blood. Also called cyanocobalamin.
Vitamin K: substance involved in normal clotting of blood.

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Whitehead: a closed comedo. See: Closed-comedo-“maturation-arrest” acne

This content taken from the book Acne Rx.

Acne Rx
This paperback book by James E Fulton, Jr. M.D. Ph.D. gets into what acne really is and how to eliminate its devastating effects.
$21.95
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